Background: Familial combined hypolipidemia, a Mendelian condition characterized by substantial reductions in all 3 major lipid fractions, is caused by mutations that inactivate the gene angiopoietin - like 3 (ANGPTL3). (sanger.ac.uk)
Research conducted soon after, however, showed that the yellow lipid fraction extracted from yellow - orange vegetables possessed the same activity.12 These vegetables contain betacarotene and other carotenoids that humans and animals can convert into retinol, the functional form of vitamin A found in animal products. (westonaprice.org)
«While MR studies have been successful in solving the causal relevance of major lipids in coronary heart disease (LDL - C and TG, yes, and HDL - C, no), it seems that other approaches are required to further evaluate the causal relevance of each of these lipid fractions in association with T2D. (sciencedaily.com)