It was hypothesized that silver toxicity, as manifested by liver necrosis in laboratory rats, was due to silver induced inhibition of the synthesis of the seleno - enzyme glutathione peroxidase. (clspress.com)
Four also had extensive liver necrosis, and two had cancer — leukemia in one case, lung cancer in the other. (sciencemag.org)
Larger ingestions can result in acute liver necrosis and liver failure. (petpoisonhelpline.com)