These may only produce local irritation, but some dogs have been reported to develop systemic reactions to the different proteins present in the saliva of these biting flies. (mypetneedsthat.com)
But local irritation at the site of the bite is likely a common occurrence for both humans and pets and the irritation is likely to occur in either host. (goodnewsforpets.com)
Some dogs may show local irritation if a groomer uses a shampoo containing an ingredient they are sensitive to. (petbusiness.com)