The solid black line is the global annual mean and the solid red line is the five - year lowess smooth, i.e. a non-parametric regression analysis that relies on a k - nearest - neighbor model. (en.wikipedia.org)
Monthly SSTA (°C) and PDO values were smoothed with a 25 - month lowess smooth. (journals.plos.org)
The mean log2 ratios for each spot were normalized using the LOWESS curve - fitting equation on a print - tip specific basis to allow for differences among the four printing pins used during array manufacturing. (molvis.org)