The trial, published in Circulation Research, was designed to test the feasibility and side effects of a genetically - enhanced stem cell therapy to repair and regenerate lung blood vessels in PAH. (sciencedaily.com)
In lab experiments with human lung blood vessel cells, the researchers found that low - oxygen conditions induced the expression of the oxygen - sensitive gene regulator HIF2alpha, which in turn increased levels of VE - PTP. (sciencedaily.com)
Additionally, developing immature worms can set off a severe, inflammatory response in the smaller lung blood vessels, in the airways and in the lung tissue itself1. (pethealthnetwork.com)