The phrase "major determinant" refers to the main factor or element that has the most influence or impact on something. It is the key thing that decides or shapes the outcome or result. Full definition
New York has slowly begun to listen to parents by not putting test scores on students» permanent records and not using tests as major determinants of whether students go to the next grade. (edimprovement.org)
Food is one of the most major determinants in your health. (mindbodygreen.com)
Reduced levels of leptin and thyroid hormone (T3) have often been considered as major determinants of AT (7, 8, 9). (alivebynature.com)