What is it: Clothing - to - skin (or skin - to - skin) friction can cause major irritation, often in the form of inflamed red welts. (dailyburn.com)
Cross Reactivity: Removing all grains from your diet may seem severe but the problem is when a person has a damaged and leaky gut lining any food resembling gluten can cause major irritation. (grassfedgirl.com)
It's the kind of thing that starts off as a quibble but turns into a major irritation for someone like me because I'm so f-cking petty. (laineygossip.com)