The phrase "major stake" refers to a significant ownership or financial interest in a company or investment. It means that someone has a large portion or control over the resources or assets involved. Full definition
Scientists hold major stakes in several companies (see table below). (sciencemag.org)
They can both play care free this coming week while others will be playing for major stakes.. (allsportsseries.com)
Companies who have major stakes in the voice assistant race have all poured millions into making their individual technologies better, more capable, and smarter than ever before. (techtimes.com)