The phrase "malignant glioma" refers to a type of cancer that starts in the brain. It is a serious and aggressive form of tumor that can grow and spread quickly, often causing severe health problems. Full definition
«When combined with systemic administration of ganciclovir, rats with malignant glioma lived significantly longer than rats that did not receive this treatment.» (sciencedaily.com)
Treatment of malignant glioma using gene transfer modalities typically consists of surgical debulking of the tumor mass followed by the administration of the viral vectors into the brain tissue surrounding the tumor cavity. (clinicaltrials.gov)
The article reviews current literature on the use of adoptive immunotherapy for malignant gliomas as well as the the concept of antitumor activity mediated by CIK cells. (neuro-central.com)