These mutations could become therapeutic targets because there are already drugs blocking the activity of these genes which may be useful in complicated cases of mantle cell lymphoma. (sciencedaily.com)
It is also often mutated in other common B cell tumors, such as mantle cell lymphoma. (sciencedaily.com)
Management strategies for patients with mantle cell lymphoma continue to demonstrate pendulum - like swings between those appropriate for low - grade lymphoma, and those appropriate for very aggressive lymphoma. (cancernetwork.com)