In addition, we wished to confirm whether or not GSDs with CDRM had lower serum vitamin E concentrations than other dogs, since this vitamin had been associated with a number of neurodegenerative diseases in other species. (siriusdog.com)
Production of this molecule is increased, for example, in situations of obesity, dyslipidaemias, lipodystrophies, hypercholesterolemia, insulin resistance (significant diabetes) and alcoholism, as well as in neurodegenerative diseases such as Alzheimer's and Multiple Sclerosis. (sciencedaily.com)
«While these findings are specific to HD and PD, these two diseases are sufficiently distinct to suggest that the observed pattern of differential gene activity may likely be observed in other neurodegenerative diseases of the central nervous system, including Alzheimer's disease and Chronic Traumatic Encephalophathy (CTE).» (sciencedaily.com)