In contrast, adult stem cells are derived from mature tissue, typically from bone marrow, but increasingly from most organs. (jamanetwork.com)
The «ink» is a clear gel mixture of mature tissue cells, immature stem cells and polymers designed to mimic real tissues» consistency. (discovermagazine.com)
One chief challenge is upregulating HDR in mature tissues, as this process is necessary to precisely edit point mutations. (blog.addgene.org)