Katherine was part of ground - breaking research in 2016 that found that inflammation in melanoma tumours could impact on the immune system's anti-cancer responses. (onjcancercentre.org)
The afternoon of the second day focused on somatic changes in melanoma, that is changes that occur in the tumour itself, and this session saw talks from ESR07 Sofia Chen on the mutational landscape of primary melanoma tumours; ESR08 Catarina Salgado on DNA hydroxymethylation (a form of regulation) in melanoma and naevi; and ESR10 Adriana Sanna on epigenetic regulation (reversible changes to the DNA which can turn genes on / off) of melanoma cell phenotypes. (melgen.org)
Early stages of clinical testing, published in the New England Journal of Medicine, suggest that it may help to shrink advanced melanoma tumours with BRAF faults. (cancerresearchuk.org)