They demonstrated that in the absence of SERT, antidepressants accumulate gradually in the plasma membrane microdomains of glioma cells. (sciencedaily.com)
These differences correlated with the observation that the B - subunit associated with Triton X-100-resistant membranes in HeLa cells, but not in monocyte - derived cells, suggesting that retrograde targeting to the biosynthetic / secretory pathway required association with specialized microdomains of biological membranes. (science.institut-curie.org)
Since most neurons receive thousands of synaptic inputs, the neuronal membrane is a mosaic of specialized microdomains where neurotransmitter receptors cluster in register with the corresponding presynaptic neurotransmitter release sites. (inmg.fr)