Phrases with «minor groove»

The phrase "minor groove" refers to a small and narrow space between the two strands of DNA, which looks like a valley or a gap. It's called "minor" because it is narrower compared to the larger space called the major groove. These grooves are important because they provide access to the genetic information stored in DNA, allowing proteins and other molecules to interact with the DNA and perform various functions. Full definition

Sentences with «minor groove»

  • The contribution made by individual functional groups of the G.U pair in the context of the Tetrahymena ribozyme was examined by replacement of the G.U pair with synthetic base pairs that maintain a wobble configuration, but that systematically alter functional groups in the major and minor grooves of the duplex. (science.sciencemag.org)
  • These bases interact intimately with the minor groove of the first two base pairs between the codon and anticodon, thus sensing Watson - Crick base - pairing geometry and discriminating against near - cognate tRNA. (science.sciencemag.org)
  • They correspond to DNA's major and minor grooves, where proteins interact with the DNA to carry out biological processes such as regulating gene expression. (discovermagazine.com)
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