One lit up in the presence of hydrogen peroxide, a prominent reactive oxygen species, whereas the other two acted as mitochondrial injury sensors. (scientificamerican.com)
But researchers have developed an imaging technique that shows, in real time, what happens when things start going awry — a tool that could help doctors diagnose mitochondrial injuries before they have the chance to do serious cellular damage. (scientificamerican.com)
The new findings suggest that manipulation of NAD could lead to a future therapy for acute kidney injury and also raise the possibility that mitochondrial injury and deficiency in NAD might underlie other types of organ damage, including damage that can lead to stroke or heart attack. (sciencedaily.com)