These complications are exceedingly rare but still possible with modified live virus vaccine. (vin.com)
For dogs older than 16 weeks of age, two doses of vaccine containing modified live virus (MLV) CPV, CDV, and CAV - 2 given 3 - 4 weeks apart are recommended. (vetmed.ucdavis.edu)
According to the NCSU guidelines, challenge tests have shown that vaccination with modified live virus vaccine for canine distemper has protected dogs from the disease five to seven years after inoculation. (canismajor.com)