The fluorescence spectrum is constant between pH4.5 and 9.0, which falls between the intracellular range in most cell types. (sciencedaily.com)
The Children's National research team also observed that VBP15 inhibits the transcription factor NF - κB, a key cell - signaling molecule found in most cell types that plays a role in inflammation and tissue damage. (sciencedaily.com)
Generally, reprogramming occurs over many days in most cell types, and it seems that fewer factors are introduced, longer time is required for reprogramming to occur [15]. (journals.plos.org)