Comparisons with structurally related ATPases, including superfamily I and II ATP - dependent helicases, suggest that the interaction geometry of the tandem motor domains in SecA is modulated by nucleotide binding, which is shown by fluorescence anisotropy experiments to reverse an endothermic domain - dissociation reaction hypothesized to gate binding to SecYEG. (science.sciencemag.org)
The atomic structures of the cardiac myosin motor domain, with and without bound omecamtiv mecarbil, were determined using X-ray crystallography. (science.institut-curie.org)
«Dirty secret No. 1 in Obamacare,» Norris notes: «Home visitation programs for families with young children and families expecting children»... providing parents with «knowledge of age - appropriate child development in cognitive, language, social, emotional, and motor domains... modeling, consulting, and coaching on parenting practices.» (articles.chicagotribune.com)