The scientists at IRB Barcelona depleted CPEB4 expression in mouse livers in order to study the function of this protein. (sciencedaily.com)
Researchers indicate they observed this crosstalk during development of mouse liver cells, natural human liver cells and in their bioengineered livers. (sciencedaily.com)
Now, in a new study published in the journal Cell, scientists at the Salk Institute for Biological Studies have discovered that a synthetic form of vitamin D, calcipotriol (a drug already approved by the FDA for the treatment of psoriasis), deactivates the switch governing the fibrotic response in mouse liver cells, suggesting a potential new therapy for fibrotic diseases in humans. (sciencedaily.com)