Dr. Eng was the 2006 Oppenheimer laureate when she was cited for her outstanding decade - long research on RET testing in multiple endocrine neoplasia type 2 as the paradigm for the practice of clinical cancer genetics and for her elegant work with Hartmut Neumann, MD, on the delineation of genotype and phenotypic spectra of the genes encoding succinate dehydrogenase and predisposition to pheochromocytoma and paraganglioma. (lerner.ccf.org)
Multiple endocrine neoplasia syndromes are caused by inherited genetic mutations. (merckmanuals.com)
Although the USPSTF recommends against screening in the general asymptomatic adult population, several factors substantially increase the risk for thyroid cancer, including a history of radiation exposure to the head and neck as a child, exposure to radioactive fallout, family history of thyroid cancer in a first - degree relative, and certain genetic conditions, such as familial medullary thyroid cancer or multiple endocrine neoplasia syndrome (type 2A or 2B).4 (jamanetwork.com)