No, you can make multiple reservations at the same hotel for the same dates in your name. (flyertalk.com)
Don't make multiple reservations and cancel all but one the week before you go. (canismajor.com)
I tend to book long - haul international trips using multiple reservations, as I feel that this method permits me to combine different itineraries that work for my schedule, while also enabling me to maximize accrual (and redemption) of frequent flier miles as well as get the best prices. (travelcodex.com)