Reyes and Ruohola - Baker are seeking ways to suppress the disorder's characteristic functional and structural muscle defects. (sciencedaily.com)
This has important therapeutic implications, as surgical repair will not be able to address the cellular muscle defect in HLHS patients, noted Lo. (sciencedaily.com)
To explore the impact of such smooth muscle defects on cardiac function, the scientists exercised δ - sarcoglycan knockout mice on treadmills. (hhmi.org)