These fine details may also help scientists understand how mutations in proteins can lead to disease or find protein properties that would be ideal targets for drug therapies. (sciencedaily.com)
Using data from experiments that simultaneously measure the effects of thousands of mutations, I develop computational tools to predict the functional impact of mutations in protein coding sequences. (cshl.edu)
In terms of disease, have we been wrong to focus on mutations in protein - coding DNA? (scientificamerican.com)