Tumor tissue is a diverse mix of cell types and states, so Zhang and others are characterizing the individual genomes, expression patterns, and mutational status of thousands of cells from a single tumor. (sciencemag.org)
The preclinical studies showed that the newly developed 18F - MPG allows one to noninvasive and repeatedly detect activating EGFR mutational status in mouse models of NSCLC with high sensitivity and specificity. (sciencedaily.com)
Khiabanian H, Hirshfield KM, Goldfinger M, Bird S, Stein M, Aisner J, Toppmeyer D, Wong S, Chan N, Dhar K, Gheeya J, Vig H, Hadigol M, Pavlick D, Ansari S, Ali S, Xia B, Rodriguez - Rodriguez L, Ganesan S. Inference of Germline Mutational Status and Evaluation of Loss of Heterozygosity in High - Depth, Tumor - Only Sequencing Data. (cinj.org)