They can be used as immunogens to produce antibodies against specific regions of proteins, and this eliminates the need to purify native proteins. (mybiosource.com)
Moderna's mRNA Therapeutics ™ platform builds on the discovery that modified mRNA can direct the body's cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs with therapeutic activity inside and outside of cells. (modernatx.com)
Our general approach has been to make use of structural motifs found in native proteins that are predisposed to interact with a particular binding geometry, and then further bolster these anchor points with favourable hydrophobic contacts. (biochemsoctrans.org)