The researchers say the results warrant further development of neoantigen vaccines, both alone and in combination with other immunotherapy weapons such as checkpoint inhibitors. (sciencedaily.com)
«If successful in subsequent trials, a personal vaccine has the potential to be applied to any cancer that harbors a sufficient numbers of neoantigens for vaccination.» (sciencedaily.com)
The foreignness of neoantigens means therapies based on them could induce strong, specific antitumor responses. (sciencemag.org)