«These strategies would focus on promoting myelination in the peripheral nervous system for neuropathic disease or inhibiting Schwann cell over-proliferation that occurs during formation of peripheral nerve sheath tumors like neurofibromas.» (sciencedaily.com)
An overabundance of Schwann cells in people with the genetic disorder neurofibromatosis 1 and 2 (who have mutations in the NF1 or NF2 tumor suppressor gene) has been linked to development of nerve sheath tumors. (sciencedaily.com)
For example, SRT can be used for pituitary tumors and trigeminal nerve sheath tumors in dogs, but IMRT is the preferred treatment for most dogs with these tumors, whereas SRT is the preferred treatment for most dogs with meningiomas. (cvm.ncsu.edu)