Progressive deterioration in CCD signs in control dogs likely reflects the cognitive ageing process, with cognitive and neurobiological changes observed in dogs entering middle age, and becoming more pronounced as they become geriatric [45]. (journals.plos.org)
To better understand the link between GABA and the development of stress resilience, Berton, Beck, and colleagues also devised an optogenetics - based approach to directly manipulate levels: Lifting GABA inhibition of serotonin neurons reduced social and anxiety symptoms in mice exposed to bullies and also fully prevented neurobiological changes due to stress. (sciencedaily.com)
To better understand the link between GABA and the development of stress resilience, Berton, Beck, and colleagues also devised an approach to directly manipulate levels: Lifting GABA inhibition of serotonin neurons reduced social and anxiety symptoms in mice exposed to bullies and also fully prevented neurobiological changes due to stress. (pennmedicine.org)