In a diabetic cornea, hyperglycemia disrupts DC - sensory nerve interactions, resulting in the impairment of sensory nerve regeneration post-wounding and diabetic peripheral neuropathy in the cornea. (sciencedaily.com)
The treatment of neuropathy with MMP - 13 - targeting compounds is the subject of a provisional patent filed by the MDI Biological Laboratory in January. (mdibl.org)
In the future, measuring substance P levels in the tear film might become a useful, noninvasive test for assessing the risk of peripheral neuropathy in patients with diabetes. (sciencedaily.com)