Simultaneous quantitative determination of 5 - aza - 2 ′ - deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure - response measures of nucleoside analog DNA methyltransferase inhibitors. (hopkinsmedicine.org)
Resistance is a significant problem with the ongoing use of nucleoside analogs, which when applied topically to the eye can cause serious side effects including glaucoma. (sciencedaily.com)
The team knew that the frequency and placement of the modified nucleosides in the strand changed how it folded, and hence how it interacted with the ribosome. (sciencemag.org)