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Phrases with «nucleotide changes»

The phrase "nucleotide changes" refers to alterations or modifications that occur in the building blocks of DNA or RNA. Nucleotides are the individual units that make up DNA and RNA molecules, and changes in these units can affect the genetic information contained in the molecule. These changes can have various consequences, ranging from harmless to significant impacts on organisms and their traits. Full definition

Sentences with «nucleotide changes»

  • Alpha -1-antitrypsin deficiency (A1ATD) is the most common genetic disease of the liver, and is caused by a single nucleotide change in the gene that codes for alpha -1-antitrypsin (A1AT), an enzyme inhibitor that normally protects bodily tissues. (scientificamerican.com)
  • Further analysis of this chromosomal region revealed a single nucleotide change in the ITGA10 gene, which disrupts the gene by introducing signal that prematurely ends the production of the encoded integrin subunit. (sciencedaily.com)
  • A gene is considered to have undergone positive selection when it has a relatively high ratio of nucleotide changes that lead to a change in the amino acid sequence of the corresponding protein, compared to changes that make no difference. (sciencemag.org)
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