Isaac's first major role came in 2006, when he played Joseph opposite Keisha Castle - Hughes in Catherine Hardwicke's The Nativity Story. (slantmagazine.com)
Funny, since it's said that Spider - Man «s first major role as an Avenger will be in Infinity War. (omegaunderground.com)
He began his career a mere decade ago, in his mid-twenties, with films in which he and his friends played characters based on himself and his friends (among them was Greta Gerwig, whose first major role was in his 2007 film «Hannah Takes the Stairs»). (newyorker.com)