Murchison and her team found striking similarities in tissues of origin, genetics, cancel cell mutation, and possible drug targets. (techtimes.com)
«Biologic models and early clinical evidence suggest that these fusions lead to oncogene addiction regardless of tissue of origin and, in aggregate, may be implicated in up to 1 % of all solid tumors,» wrote the study authors, led by Alexander Drilon, MD, of Memorial Sloan Kettering Cancer Center in New York. (cancernetwork.com)
«Ovarian cancer treatments have not changed much in many decades, and this may be, in part, because we have been studying the wrong tissue of origin for these cancers,» says study leader Victor Velculescu, M.D., Ph.D., a professor of oncology at the Johns Hopkins Kimmel Cancer Center. (sciencedaily.com)