«In the knot structure, C letters on the same strand of DNA bind to each other — so this is very different from a double helix, where «letters» on opposite strands recognise each other, and where Cs bind to Gs [guanines].» (scimex.org)
After incubating HeLa cells and neurons from embryonic mice with different amounts of these DNA opposite strand bits, they noted that the more DNA bits they added, the more mRNA levels increased that code for SMA protein. (sciencedaily.com)
Opposite the Strand is a newish Pret a Manger. (firstthings.com)