Interestingly, certain allelic combinations give rise to embryos that arrest early in development, while other alleles complement female sterility of the rum mutation. (genetics.org)
For example, Clone # 5 had only a 10 - bp insertion / 4 - bp deletion on one allele and a 1 - bp insertion on the other allele at the editing site. (takarabio.com)
Conversely, some indels were much larger; Clone # 3 had an 18 - bp deletion on one allele and a 228 - bp insertion on the other allele. (takarabio.com)