The research, published in Science Translational Medicine, focused on two specific types of melanoma and breast cancer, but this approach may work in other tissue types. (frontlinegenomics.com)
As with results of their earlier studies, the investigators found that the higher the expression of this protein, the more aggressive the cancer, which is determined by how the cells invade other tissue types and their ability to form tumors in laboratory models of cancers. (sciencedaily.com)
The finding made intuitive sense; researchers studying other tissue types had shown that activating mTOR can drive dormant cells out of quiescence, a necessary step for regeneration. (sciencedaily.com)