When that happens, the immune system fails to work and people get overwhelming infections. (cancerresearch.org)
The prognosis for severely infected dogs is guarded since overwhelming infection usually causes irreversible organ damage, resulting in rapid deterioration and death in spite of appropriate treatment. (lienanimal.com)
And the fatal cases were «associated with misdiagnosis or delays in seeking treatment, which resulted in overwhelming infection and various manifestations of the systemic inflammatory response syndrome.» (voxfelina.com)