A combination of whole fish and fish meal is used, aiming for a whole prey diet that includes cartilage and other parts of the protein. (herepup.com)
The best approach, of course, is to get the bigger part of your protein intake from food, and use protein shakes as an addition to your already protein - rich diet. (fitnessandpower.com)
If the changed amino acid is not in a crucial part of the protein, then there may be no adverse effect. (science.howstuffworks.com)