TPE is an apheresis (removal of impurities from blood) treatment in which plasma contaminated with damaging auto - antibodies, toxins or abnormal proteins is separated from the patient's flowing blood and exchanged with donor plasma that is returned to the patient to render the patient less susceptible to or free from immunologic attack or other pathologic processes. (vetmed.ucdavis.edu)
Despite this clinical importance, the exact pathologic process of tumor metastasis is as yet poorly understood, and deciphering the exact molecular mechanism of this process is of paramount importance to identify specific therapeutic targets for this devastating disease. (cancerres.aacrjournals.org)
Functional imaging using in vivo confocal microscopy which allows the analysis of vaso - activity phenomena during hypoxia, of ischaemia reperfusion events, or of homing cells in pathologic processes, such as tumours or inflammatory diseases. (ersroadmap.org)