Whether use entails periodic bouts of binge drinking or drug use, or daily use in smaller but still problematic quantities, substance use causes significant problems of its own, however. (psychpage.com)
In fact the outcome has been quite different with periodic bouts of volatility and risk aversion quickly evaporating. (investegate.co.uk)
If they survive this crisis, they suffer periodic bouts of hepatitis - particularly when stressed. (2ndchance.info)