"Permadeath mode" refers to a setting or feature in a video game where, if your character dies, they cannot be revived or continue playing. Full definition
There's a new permadeath mode for those who enjoy being horribly punished, and a new photo mode that will allow you to take pictures of your ship in third - person view, add filters, and adjust the lighting to your satisfaction. (pcgamer.com)
You can still resurrect characters, even in permadeath mode, but it still takes quite a few resources to do so. (gamecrate.com)
And let us not forget, the full release brings Permadeath mode to the table. (coin-drop.com)