In addition, two patients with persistent disease received additional therapy and two patients died of treatment - related toxicities. (sciencedaily.com)
Oxidative stress comes from the environment, in forms such as UV damage from the sun, or can occur as an effect of persistent disease conditions. (drvitaminsolutions.com)
«One criticism of the PARP drugs is they are not active in patients who have developed resistance to other therapies, but we found veliparib appears to be effective in some platinum - resistant patients with recurrent or persistent disease,» said Robert L. Coleman, MD, lead author of the study and professor and vice chair of clinical research at the University of Texas MD Anderson Cancer Center, Houston. (sciencedaily.com)