One of the main challenges in finding a treatment for the disease in the future is the research and development of pharmacological therapies capable of activating the Crtc1 protein, with the aim of preventing, slowing down or reverting cognitive alterations in patients. (sciencedaily.com)
«By identifying key molecular drivers within these networks, we have been able to determine potential therapeutic targets that could help us to develop the first pharmacological therapy for CAVD.» (sciencedaily.com)
The results showed that despite no change over time in the severity of illness of the patients with severe sepsis enrolled in the clinical trials, mortality rates declined significantly over 20 years, and the decline occurred without the development of new pharmacological therapies targeted to treat severe sepsis. (sciencedaily.com)