Changing a signaling molecule's phosphorylation status elicits specific changes in the molecule's activation status. (sciencedaily.com)
During infection T. gondii parasites not only alter the transcriptional profile of the host cells but also modulate host - signaling cascades at the protein level by secreting a battery of kinase and pseudokinase proteins into the host cell potentially modifying the phosphorylation status and function of many host proteins. (jcvi.org)
The phosphorylation status of all mTOR signaling proteins was determined as negative, positive, and strongly positive (+ +) depending on the presence and staining intensity of signal (Table 1). (cancerres.aacrjournals.org)