PERV genes are interwoven into the genome of pig cells, so eGenesis scientists start their work with CRISPR - Cas9, which has made editing organisms» genomes so simple high - schoolers can do it. (scientificamerican.com)
In 2015, she and colleagues in Church's lab used CRISPR to eliminate from pig cells 62 genes so potentially dangerous their very existence nixed previous efforts to turn pigs into organ donors. (scientificamerican.com)
eGenesis ships batches of these cells to China, where each de-PERV» ed pig cell is fused with a pig ovum whose own DNA has been removed. (scientificamerican.com)