Historically, cell lineage tracing studies have taken large pools of cells from mature tissues and inferred their origins retrospectively by staining the cells with vital dyes or transplanting isotopically labeled cells into donor animals. (the-scientist.com)
Their further studies showed that the human version of the enhancer causes cells that are destined to become nerve cells to divide more frequently, thereby providing a larger of pool of cells that become part of the cortex. (sciencemag.org)
«Fibroblasts make up about 50 % of all cells in the heart and therefore represent a vast pool of cells that could one day be harnessed and reprogrammed to create new muscle,» said Dr. Srivastava, who is also a professor at the University of California, San Francisco, with which Gladstone is affiliated. (gladstone.org)