Phrases with «positional cloning»

Positional cloning is a scientific method used to identify and locate specific genes or DNA sequences within a genome. It involves studying the physical position, or location, of a gene on a chromosome in order to find and clone the DNA responsible for a particular trait or disease. Full definition

Sentences with «positional cloning»

  • This study additionally demonstrates that the systematic examination of panels of biological candidate genes in large, well - characterised populations can be an effective complement to positional cloning approaches. (sanger.ac.uk)
  • We have used mouse models as an entry point to identify molecules that are essential for normal retinal development and function through positional cloning efforts. (jax.org)
  • The search culminated in a 1994 Science paper reporting the isolation of BRCA1 by positional cloning. (science.sciencemag.org)
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