Early symptoms of potassium depletion, or hypokalemia, include muscle cramping or fatigue, especially during exercise. (healthyeating.sfgate.com)
I am on Lasix myself, and I have experienced the symptoms of real potassium depletion: severe muscle cramps. (KetoDietApp.com)
According to the Natural Medicines Comprehensive Database, the potential side effects of senna use may include abdominal pain and discomfort, cramps, bloating, gas, nausea, and diarrhea; excessive use can lead to potassium depletion and other electrolyte abnormalities, which can trigger muscle spasms and an abnormal heart rhythm. (health.com)