However, sophisticated algorithms are often combined with Affymetrix probe set definitions derived from obsolete genome and transcriptome information. (cmbn.no)
To identify genes that cluster together under the tested conditions, we excluded probe sets with a standard deviation in expression values of < log2 (0.45) from the vector mean. (journals.plos.org)
Our solution significantly increases the reliability of probe sets and also provides the opportunity for examining results based on different gene / transcript / exon definitions. (cmbn.no)